FIB-4 Liver Fibrosis Score

A simple blood-test score that estimates the likelihood of advanced liver fibrosis.

Awaiting clinical review. Results are based on validated formulas but pending physician verification.

How this is calculated

FIB-4 = (age × AST) / (platelets × √ALT). Validated cut-offs flag low risk (<1.30) vs high likelihood of advanced fibrosis (>2.67), with an age-adjusted upper cut-off of 2.0 from age 65.

Sources

  1. Sterling RK, et al. Development of a simple noninvasive index to predict significant fibrosis in HIV/HCV coinfection. Hepatology 2006.
  2. Ishiba H, et al. Novel age-based FIB-4 cut-offs for NAFLD. J Gastroenterol 2019.
This calculator is for educational purposes and is not a substitute for professional medical advice, diagnosis, or treatment. The result is based on standard clinical formulas applied to the values you entered — your individual situation may need adjustments your doctor can make. Never disregard professional medical advice or delay seeking it because of something you read or calculated on healthcalculus.

Related reading

Understanding your CBC report